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Pharmaceutical laboratory at the Virgen de la Arrixaca University Hospital

Spain

IDOM has developed the basic and detailed engineering as well as the project management of a pharmaceutical laboratory project at the Virgen de la Arrixaca University Hospital in Murcia. The facilities are intended for the production of radio injectable drugs for molecular diagnosis and therapy using positron emission tomography (PET). The facilities are divided into four areas: administrative, production, radiation and machinery. The building has 80 m2 for offices, a production area of ​​250 m2 with laboratories/clean rooms classified as class C (ISO-7) for the installation of synthesis cells classified as class B & A (ISO-5). On the other hand, there is an area of ​​about 100 m2 for the installation of the cyclotron and its systems. The technical room has an area of ​​about 120 m2.

The administrative area is 80 m2 and is divided into two different zones. One area is intended for meetings and the other is a common area with bathrooms and machine room. It is a metal structure, covered with a concrete slab.

In the production area the products are manipulated to obtain the final drug. It consists of three laboratories equipped with hot cells supplied by COMECER. This area has different warehouses, two quality control laboratories, offices, shipping area and changing rooms. It is designed with a metal structure above which the machinery room is located.

The radiation area is the area where the cyclotron is located (supplied by General Electric) and it has a control room and the decay zone. In both areas solid and liquid wastes are handled until completely inertized. This area is constructed of reinforced concrete with thicknesses that reaches 2 meters.

The machinery area, located on the upper floor, includes UTAS, filters, fans, part of the radio protection system, the boiler and sensors. It is built with a metal structure covered with sandwich panels.

In general, the building has a radiation alarm based on environmental and ventilation sensors that meet the requirements of the Spanish Medicines Agency and relevant regulations for clean rooms (UNE-EN_ISO-14644). This building has been validated by the Nuclear Safety Council (CSN) and by the Spanish Medicines Agency prior to its launch.

Health

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SCOPE:
Detailed Engineering & Works Supervision
Detailed Engineering & Works Supervision

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